Updated 10/24/2025
What are GLP-1 medications?
GLP-1 receptor agonists like semaglutide and tirzepatide mimic natural hormones that regulate appetite and blood sugar levels.
What’s the difference between semaglutide and tirzepatide?
Semaglutide targets GLP-1 receptors. Tirzepatide targets both GLP-1 and GIP receptors.
Is compounded semaglutide FDA-approved?
No. Compounded semaglutide is not FDA-approved and must be prescribed by a licensed provider.
Is compounded tirzepatide FDA-approved?
No. Compounded tirzpeatide is not FDA-approved and must be prescribed by a licensed provider.
Will my medication include additives? If so, what do the different additives do?
Possibly. Additives like B12, B6, NAD+, and glycine may be included to support comfort and minimize side effects.
Niacin (Vitamin B3)
Helps reduce fatigue and may support metabolic function.
Pyridoxine (Vitamin B6)
Known for its anti-nausea properties. Often included to reduce queasiness—especially during early treatment phases.
Cyanocobalamin (Vitamin B12)
A synthetic B12 used to support energy, red blood cell production, and metabolism. It's cost-effective and stable.
Methylcobalamin (Vitamin B12)
The bioactive form of B12. Supports nerve health, brain clarity, and energy metabolism—no conversion needed in the liver.
NAD+ (Nicotinamide Adenine Dinucleotide)
A coenzyme that helps your cells generate energy. Added to reduce fatigue and support metabolic function.
Glycine
An amino acid that may reduce injection site irritation and promote restful sleep. It also supports detox pathways and collagen synthesis.
These additives are selected by providers on a case-by-case basis depending on your individual needs and goals.
Can I request a medication without additives? In your intake form, you can indicate if you would like to avoid certain or all additives. A provider may recommend additives; however, if personalized your medication is in your best interest for avoiding side effects and reaching your goals. (We may be doing this with our new pharmacy and provider)
What are the side effects of GLP-1s?
Common side effects include nausea, vomiting, constipation, and appetite changes. Providers often use a “start low and go slow” approach to help minimize side effects.
What should I eat while on semaglutide?
Eat small, protein-rich meals and stay hydrated. Avoid greasy, sugary, or carbonated foods. Support digestion with gentle meals and regular hydration.
Do GLP-1 meds need to be refrigerated?
Yes. Store between 36°F and 46°F. Do not freeze. Use a cooler for travel.
Can I switch from tirzepatide to semaglutide OR semaglutide to tirzepatide?
Yes, with guidance from a licensed provider who may adjust dosing according.